Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.73 |
| ▸ | MMP2 | P08253 | 2/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PTPRA | P18433 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL27459414 | 1.00 | SLC7A5 (0.73) | SLC7A5MMP2PTGS1ALPIPKM | |
| Tyrosine SCHEMBL27497255 | 0.94 | SLC7A5 (0.69) | SLC7A5MMP2PTGS1ALPIPKM | |
| SCHEMBL503312 | 0.94 | SLC7A5 (0.61) | SLC7A5MMP2PTGS1ALPIPKM | |
| SCHEMBL26444 | 0.94 | SLC7A5 (0.61) | SLC7A5MMP2PTGS1ALPIPKM | |
| SCHEMBL26443 | 0.94 | SLC7A5 (0.61) | SLC7A5MMP2PTGS1ALPIPKM | |
| SCHEMBL437181 | 0.94 | SLC7A5 (0.61) | SLC7A5MMP2PTGS1ALPIPKM | |
| 4-Nitrobenzoic Acid SCHEMBL11907092 | 0.93 | SLC7A5 (0.63) | SLC7A5MMP2PTGS1ALPIPKM | |
| 4-Nitrobenzoic Acid SCHEMBL11907095 | 0.93 | SLC7A5 (0.63) | SLC7A5MMP2PTGS1ALPIPKM | |
| Water SCHEMBL4754409 | 0.92 | SLC7A5 (0.59) | SLC7A5MMP2PTGS1ALPIPKM | |
| Water SCHEMBL4754408 | 0.92 | SLC7A5 (0.59) | SLC7A5MMP2PTGS1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022962-A9 | BUTYRYL-TYROSINYL SPERMINE, ANALOGS THEREOF AND METHODS OF PREPARING AND USING SAME | — | 1996-10-03 | — | — | WO | disclosed |
| WO-1996022962-A1 | BUTYRYL-TYROSINYL SPERMINE, ANALOGS THEREOF AND METHODS OF PREPARING AND USING SAME | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1996-08-01 | — | — | WO | disclosed |