SCHEMBL2741244

SCHEMBL2741244

COc1c(C)c(C(C)(C)C)c(O)c(C(C)(C)C)c1C

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.35
CA1 P00915 1/20 0.35
TDP1 Q9NUW8 2/20 0.31
ALDH1A1 P00352 2/20 0.30
CYP3A4 P08684 2/20 0.30
POLB P06746 1/20 0.30
TYR P14679 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
MAPT P10636 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2741243 0.86 CA1 (0.33) CA2CA1
SCHEMBL14969580 0.86 CA2 (0.35) CA2CA1TDP1ALDH1A1CYP3A4
SCHEMBL13052396 0.84 TDP1 (0.34) CA2CA1TDP1
SCHEMBL785152 0.82 CA1 (0.33) CA2CA1
SCHEMBL784968 0.81 CA2 (0.35) CA2CA1TDP1ALDH1A1CYP3A4
SCHEMBL16363485 0.79 CA1 (0.34) CA2CA1TDP1
SCHEMBL13388145 0.77 CA1 (0.33) CA2CA1
SCHEMBL12377549 0.77 ABCB1 (0.37) CA2CA1
SCHEMBL5589207 0.77 CA1 (0.39) CA2CA1TDP1CYP3A4MAPT
SCHEMBL7907472 0.76 CA2 (0.36) CA2CA1ALDH1A1POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9523060-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2016-12-20 US disclosed
US-9523060-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2016-12-20 US disclosed
US-20150159109-A1 Lubricant Oil Compositions POLNOX CORPORATION 2015-06-11 US disclosed
US-20150159109-A1 Lubricant Oil Compositions POLNOX CORPORATION 2015-06-11 US disclosed
US-8927472-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2015-01-06 US disclosed
US-8927472-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2015-01-06 US disclosed
US-20130130955-A1 LUBRICANT OIL COMPOSITIONS POLNOX CORPORATION (US) 2013-05-23 US disclosed
US-20130130955-A1 LUBRICANT OIL COMPOSITIONS POLNOX CORPORATION (US) 2013-05-23 US disclosed
US-20120004150-A1 Lubricant Oil Compositions POLNOX CORPORATION 2012-01-05 US disclosed
US-7678877-B2 Process for the synthesis of polyalkylphenol antioxidants POLNOX CORPORATION (US) 2010-03-16 US disclosed
US-20070161522-A1 Lubricant oil compositions POLNOX CORPORATION 2007-07-12 US disclosed
US-20070149660-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2007-06-28 US disclosed