Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | LPL | P06858 | 2/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15417042 | 0.78 | RARB (0.52) | RARBTRPV1MAPTKDM4EMEN1 | |
| SCHEMBL8913554 | 0.77 | RARB (0.45) | RARBTRPV1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9484152 | 0.77 | LPL (0.46) | LPLLIPGPPARAPPARG | |
| SCHEMBL8966317 | 0.77 | TRPV1 (0.44) | RARBTRPV1LPLLIPGMAPT | |
| SCHEMBL8867238 | 0.76 | ERN1 (0.40) | SMN1; SMN2MEN1ALDH1A1GAAHPGD | |
| SCHEMBL6114969 | 0.73 | TRPV1 (0.58) | TRPV1TLR7MEN1KMT2A | |
| SCHEMBL6114625 | 0.73 | TRPV1 (0.58) | TRPV1TLR7MEN1KMT2A | |
| SCHEMBL6114605 | 0.73 | TRPV1 (0.58) | TRPV1TLR7MEN1KMT2A | |
| SCHEMBL6115263 | 0.73 | TRPV1 (0.58) | TRPV1TLR7MEN1KMT2A | |
| SCHEMBL6114751 | 0.73 | TRPV1 (0.58) | TRPV1TLR7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1100419-A | 3-quinolyl-substituted dihydropyridines, process for their preparation and their use in medicaments | BAYER AG (DE) | 1995-03-22 | — | — | CN | disclosed |