Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 8/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.47 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6300057 | 0.84 | CCKBR (0.59) | CCKBRKCNH2PSEN1PSEN2APH1B | |
| SCHEMBL7094137 | 0.82 | KCNH2 (0.73) | CCKBRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8617432 | 0.81 | HDAC3 (0.75) | CCKBRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29437013 | 0.81 | HDAC3 (0.75) | CCKBRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29499518 | 0.81 | HDAC3 (0.75) | CCKBRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6300291 | 0.81 | SCN9A (0.61) | CCKBRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7089563 | 0.80 | KCNH2 (0.60) | CCKBRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8609997 | 0.80 | CCKBR (0.53) | CCKBRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4984898 | 0.75 | PSEN1 (0.75) | CCKBRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27505370 | 0.75 | PSEN1 (0.75) | CCKBRHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1074926-C | Antiarrhythmic benzodiazepines | MERCK & CO INC (US) | 2001-11-21 | — | — | CN | disclosed |