Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | GMNN | O75496 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25419410 | 0.93 | MAPK1 (0.53) | MAPK1MAPTLMNAALDH1A1L3MBTL1 | |
| SCHEMBL27415189 | 0.93 | LMNA (0.47) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL29329049 | 0.92 | LMNA (0.48) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL22645885 | 0.92 | LMNA (0.48) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL18641655 | 0.92 | LMNA (0.48) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL27415170 | 0.91 | LMNA (0.51) | MAPTLMNAALDH1A1PRKCAPRKCE | |
| SCHEMBL22920335 | 0.90 | MAPT (0.56) | MAPK1MAPTLMNAALDH1A1L3MBTL1 | |
| SCHEMBL27415123 | 0.89 | MAPK1 (0.41) | MAPK1MAPTLMNAALDH1A1L3MBTL1 | |
| SCHEMBL31664164 | 0.89 | MAPK1 (0.51) | MAPK1MAPTLMNAALDH1A1L3MBTL1 | |
| SCHEMBL31664158 | 0.89 | MAPK1 (0.51) | MAPK1MAPTLMNAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024119037-A1 | NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES COMPRISING THE SAME | UNIVERSITY OF CINCINNATI (US) | 2024-06-06 | — | — | WO | disclosed |