Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623006 | 0.99 | KMT2A (0.43) | KMT2AKDM4EALDH1A1TDP1MEN1 | |
| SCHEMBL8623000 | 0.99 | KMT2A (0.43) | KMT2AKDM4EALDH1A1TDP1MEN1 | |
| SCHEMBL27419578 | 0.87 | MAPT (0.36) | KMT2AALDH1A1MEN1MAPTMAPK1 | |
| SCHEMBL8618608 | 0.87 | BTN3A1 (0.37) | KMT2AMEN1 | |
| SCHEMBL8620223 | 0.86 | MAPT (0.36) | KMT2AALDH1A1MEN1MAPTMAPK1 | |
| SCHEMBL8620225 | 0.86 | MAPT (0.36) | KMT2AALDH1A1MEN1MAPTMAPK1 | |
| SCHEMBL8624770 | 0.85 | PPARA (0.42) | — | |
| SCHEMBL8624765 | 0.85 | PPARA (0.42) | — | |
| SCHEMBL27395211 | 0.80 | FDPS (0.36) | FDPS | |
| SCHEMBL8618638 | 0.80 | NPSR1 (0.40) | KMT2AALDH1A1TDP1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1089614-A | Alpha-phosphonosulfonate squalene synthetase inhibitors and method | SQUIBB & SONS INC (US) | 1994-07-20 | — | — | CN | disclosed |