SCHEMBL2741580

SCHEMBL2741580

C=CC(=O)OCC(=O)OCC(C)(COC(=O)COC(=O)C=C)COC(=O)COC(=O)C=C

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
TP53 P04637 3/20 0.46
HIF1A Q16665 3/20 0.46
CYP3A4 P08684 2/20 0.46
MAPK1 P28482 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TSHR P16473 7/20 0.42
THRB P10828 2/20 0.42
HPGD P15428 1/20 0.41
HSD17B10 Q99714 2/20 0.41
LMNA P02545 1/20 0.32
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18516817 0.89 ALDH1A1 (0.46) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL39919 0.86 ALDH1A1 (0.59) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL10175678 0.85 ALDH1A1 (0.43) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL27055855 0.81 ALDH1A1 (0.47) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL27055890 0.81 ALDH1A1 (0.47) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL13739822 0.81 ALDH1A1 (0.43) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL10175669 0.81 ALDH1A1 (0.46) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL27055876 0.80 ALDH1A1 (0.46) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL27055872 0.80 ALDH1A1 (0.46) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL27055862 0.80 ALDH1A1 (0.46) ALDH1A1TP53HIF1ACYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9663671-B2 Curable composition for imprints and method of storing the same FUJIFILM CORPORATION (JP) 2017-05-30 US disclosed
US-8933144-B2 Curable composition for imprint, pattern-forming method and pattern FUJIFILM CORPORATION (JP) 2015-01-13 US disclosed
US-8877828-B2 Method for producing curable composition for imprints FUJIFILM CORPORATION (JP) 2014-11-04 US disclosed
US-8851624-B2 Maintenance liquid FUJIFILM CORPORATION (JP) 2014-10-07 US disclosed
US-20140255662-A1 CURABLE COMPOSITION FOR IMPRINT, PATTERN-FORMING METHOD AND PATTERN FUJIFILM CORPORATION (JP) 2014-09-11 US disclosed
US-8820541-B2 Method for producing curable composition for imprints FUJIFILM CORPORATION (JP) 2014-09-02 US disclosed
US-20140227493-A1 CURABLE COMPOSITION FOR IMPRINTS AND METHOD OF STORING THE SAME FUJIFILM CORPORATION (JP) 2014-08-14 US disclosed
US-8783823-B2 Maintenance liquid FUJIFILM CORPORATION (JP) 2014-07-22 US disclosed
US-20140048754-A1 MAINTENANCE LIQUID FUJIFILM CORPORATION (JP) 2014-02-20 US disclosed
US-20120207943-A1 METHOD FOR PRODUCING CURABLE COMPOSITION FOR IMPRINTS FUJIFILM CORPORATION (JP) 2012-08-16 US disclosed
US-20120076948-A1 METHOD FOR PRODUCING CURABLE COMPOSITION FOR IMPRINTS FUJIFILM CORPORATION (JP) 2012-03-29 US disclosed
US-20120004385-A1 MAINTENANCE LIQUID FUJIFILM CORPORATION (JP) 2012-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004385-A1 MAINTENANCE LIQUID EED, PRDM9, DOT1L ALDH1A1 1272/4885TP53 1201/4885HIF1A 4802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.