Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 20/20 | 0.54 |
| ▸ | JAK1 | P23458 | 19/20 | 0.54 |
| ▸ | JAK2 | O60674 | 13/20 | 0.54 |
| ▸ | TYK2 | P29597 | 11/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27416768 | 0.92 | JAK3 (0.57) | JAK3JAK1JAK2TYK2 | |
| SCHEMBL27416297 | 0.91 | JAK3 (0.56) | JAK3JAK1JAK2TYK2 | |
| SCHEMBL31711631 | 0.90 | JAK3 (0.61) | JAK3JAK1JAK2TYK2 | |
| SCHEMBL27414995 | 0.90 | JAK3 (0.61) | JAK3JAK1JAK2TYK2 | |
| SCHEMBL31711649 | 0.84 | JAK3 (0.53) | JAK3JAK1JAK2TYK2 | |
| SCHEMBL27417948 | 0.84 | JAK3 (0.53) | JAK3JAK1JAK2TYK2 | |
| SCHEMBL27417930 | 0.80 | JAK1 (0.52) | JAK3JAK1JAK2TYK2 | |
| SCHEMBL31711654 | 0.80 | JAK3 (0.59) | JAK3JAK1JAK2TYK2 | |
| SCHEMBL27414876 | 0.80 | JAK3 (0.59) | JAK3JAK1JAK2TYK2 | |
| SCHEMBL27416366 | 0.80 | JAK3 (0.56) | JAK3JAK1JAK2TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137548-A2 | INHIBITORS OF JAK2 | Llydaw Therapeutics, Inc. (US) | 2024-06-27 | — | — | WO | disclosed |