Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810450 | 1.00 | CA12 (0.53) | CA12CA1CA2TYRCA7 | |
| SCHEMBL3344873 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPTHTTTDP1 | |
| SCHEMBL3348480 | 0.83 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3344879 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPTHTTTDP1 | |
| SCHEMBL27473724 | 0.83 | NR1H4 (0.39) | CA12CA1CA2TYRCA7 | |
| SCHEMBL3348476 | 0.83 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| E-Methyl Cinnamate SCHEMBL27467234 | 0.80 | CA12 (0.67) | CA12CA1CA2TYRCA7 | |
| SCHEMBL3344787 | 0.80 | HDAC3 (0.44) | KDM4EKMT2AALDH1A1HTTCYP1A2 | |
| SCHEMBL3344782 | 0.80 | HDAC3 (0.44) | KDM4EKMT2AALDH1A1HTTCYP1A2 | |
| SCHEMBL1267986 | 0.79 | HCAR2 (0.61) | CA12CA1CA2TYRCA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1281644-C | Photoactive copolymer | ROLIC AG (CH) | 2006-10-25 | — | — | CN | disclosed |
| CN-1501948-A | Photoactive copolymer | — | 2004-06-02 | — | — | CN | disclosed |
| CN-1097051-C | N-heteroaryl-pyridinesulfonamide derivatives and their use as endothelin antagonists | ZENECA LTD (GB) | 2002-12-25 | — | — | CN | disclosed |
| CN-1192739-A | N-heteroaryl-pyridinesulfonamide derivatives and their use as endothelin antagonists | ZENECA LTD (GB) | 1998-09-09 | — | — | CN | disclosed |