Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PLG | P00747 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13086081 | 1.00 | LMNA (0.55) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL13086035 | 1.00 | LMNA (0.55) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL13433722 | 1.00 | — | — | |
| SCHEMBL13952081 | 1.00 | LMNA (0.55) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL6674553 | 0.97 | — | — | |
| SCHEMBL5574144 | 0.88 | — | — | |
| SCHEMBL17178094 | 0.84 | TSHR (0.41) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL20959981 | 0.82 | LMNA (0.40) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL14209341 | 0.81 | PAOX (0.42) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL11491420 | 0.77 | LMNA (0.48) | LMNAKMT2ATHRBMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112119-A1 | DEGRADER FOR DECOMPOSING CMET PROTEIN, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 이노큐어테라퓨틱스 | 2024-05-30 | — | — | WO | disclosed |