Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | MELK | Q14680 | 1/20 | 0.41 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31427032 | 0.75 | ALDH1A1 (0.55) | LRRK2BTKPARP1TLR8POLB | |
| SCHEMBL1150533 | 0.75 | PDPK1 (0.38) | TLR8TLR7DYRK1APIM1DYRK2 | |
| SCHEMBL30593080 | 0.75 | PDPK1 (0.38) | TLR8TLR7DYRK1APIM1DYRK2 | |
| Hydrochloric Acid SCHEMBL31427020 | 0.74 | ALDH1A1 (0.54) | LRRK2BTKPARP1TLR8POLB | |
| SCHEMBL14771286 | 0.74 | CHEK1 (0.49) | JAK2RPS6KA3MELKSTK24CHEK1 | |
| SCHEMBL1944414 | 0.72 | — | — | |
| SCHEMBL1043404 | 0.69 | KDM4E (0.44) | MAPTMEN1KMT2A | |
| SCHEMBL30386054 | 0.68 | ALDH1A1 (0.58) | JAK2RPS6KA3MELKSTK24CHEK1 | |
| SCHEMBL29039486 | 0.68 | ALDH1A1 (0.58) | JAK2RPS6KA3MELKSTK24CHEK1 | |
| SCHEMBL12336177 | 0.67 | KCNA5 (0.51) | MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024126987-A1 | INHIBITORY COMPOUNDS | STORM THERAPEUTICS LIMITED (GB) | 2024-06-20 | — | — | WO | disclosed |