Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 7/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30296230 | 0.87 | EDNRA (0.45) | EDNRAAGTR1BRD4EDNRB | |
| SCHEMBL25084422 | 0.87 | EDNRA (0.45) | EDNRAAGTR1BRD4EDNRB | |
| SCHEMBL30171018 | 0.85 | EDNRA (0.56) | EDNRAAGTR1EDNRBCCNT1CDK9 | |
| SCHEMBL30296194 | 0.79 | EDNRA (0.51) | EDNRAAGTR1EDNRB | |
| SCHEMBL30844599 | 0.78 | EDNRA (0.46) | EDNRAAGTR1EDNRB | |
| SCHEMBL31229092 | 0.77 | EDNRA (0.57) | EDNRAAGTR1EDNRB | |
| SCHEMBL31229191 | 0.77 | EDNRA (0.57) | EDNRAAGTR1EDNRB | |
| SCHEMBL4287935 | 0.76 | EDNRA (0.61) | EDNRAAGTR1EDNRB | |
| SCHEMBL30295907 | 0.74 | EDNRA (0.47) | EDNRAAGTR1EDNRB | |
| SCHEMBL30844585 | 0.74 | EDNRA (0.47) | EDNRAAGTR1EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393920-A1 | AROMATIC RING-CONTAINING BIOLOGICAL ANTAGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |