SCHEMBL27420721

SCHEMBL27420721

CCOC(=O)C1NC(=O)C(NC(=O)OCC2c3ccccc3-c3ccccc32)C(c2ccc3ccccc3c2)CCC1CCN

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.33
▸ EPHX2 P34913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27420738 0.91 KMT2A (0.39) KMT2ATDP1
SCHEMBL27420747 0.88 KMT2A (0.42) KMT2ATDP1EPHX2
SCHEMBL27420878 0.86 KMT2A (0.38) KMT2ATDP1
SCHEMBL27420809 0.86 KMT2A (0.38) KMT2ATDP1
SCHEMBL27420844 0.84 KMT2A (0.41) KMT2ATDP1EPHX2
SCHEMBL27420215 0.81 FABP7 (0.38) KMT2ATDP1EPHX2
SCHEMBL27420200 0.81 FABP7 (0.38) KMT2ATDP1EPHX2
SCHEMBL27420760 0.81 KMT2A (0.41) KMT2ATDP1EPHX2
SCHEMBL27420775 0.81 KMT2A (0.41) KMT2ATDP1EPHX2
SCHEMBL27420855 0.81 NAAA (0.42) KMT2ATDP1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024092256-A2 PEPTIDE-ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-05-02 — — WO disclosed
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