Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 10/20 | 0.64 |
| ▸ | PI4K2B | Q8TCG2 | 10/20 | 0.64 |
| ▸ | PI4K2A | Q9BTU6 | 10/20 | 0.64 |
| ▸ | PI4KB | Q9UBF8 | 10/20 | 0.64 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PIP4K2A | P48426 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.41 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11862452 | 0.88 | PI4KB (0.69) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL18292155 | 0.79 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL11829935 | 0.78 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL30974263 | 0.77 | ADORA2A (0.47) | PI4KAPI4K2BPI4K2API4KBMEN1 | |
| SCHEMBL27422698 | 0.77 | ADORA2A (0.47) | PI4KAPI4K2BPI4K2API4KBMEN1 | |
| SCHEMBL11813800 | 0.76 | PI4KA (0.62) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL6354390 | 0.75 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL21638051 | 0.74 | PI4KA (0.72) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| Hydrochloric Acid SCHEMBL8595785 | 0.74 | PI4KA (0.71) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL3538512 | 0.73 | PI4KA (0.77) | PI4KAPI4K2BPI4K2API4KBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129780-A1 | BENZIMIDAZOLE DERIVATIVES AS GPX4 INHIBITORS | SONATA THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024129780-A1 | BENZIMIDAZOLE DERIVATIVES AS GPX4 INHIBITORS | SONATA THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |