Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 5/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20756869 | 0.90 | KDM2B (0.33) | TLR9TLR8TLR7KDM2B | |
| SCHEMBL27400932 | 0.88 | OPRM1 (0.33) | TLR9TLR8TLR7KCNH2OPRM1 | |
| SCHEMBL25046007 | 0.84 | MAP3K12 (0.33) | OPRM1OPRL1 | |
| SCHEMBL23337914 | 0.84 | MAP3K12 (0.33) | OPRM1OPRL1 | |
| SCHEMBL24844831 | 0.83 | KDM2B (0.39) | KCNH2KDM2B | |
| SCHEMBL26000758 | 0.83 | OPRM1 (0.33) | OPRM1OPRL1 | |
| SCHEMBL27400906 | 0.83 | TLR9 (0.31) | TLR9TLR8TLR7 | |
| SCHEMBL25672748 | 0.80 | OPRM1 (0.35) | TLR9TLR8TLR7OPRM1OPRL1 | |
| SCHEMBL16980439 | 0.80 | DPP4 (0.41) | OPRM1OPRL1KDM2B | |
| SCHEMBL20756988 | 0.80 | OPRL1 (0.38) | OPRM1OPRL1KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129763-A1 | MODULATORS OF TNF-α ACTIVITY | FORWARD THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |