Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.54 |
| ▸ | NT5E | P21589 | 3/20 | 0.47 |
| ▸ | PDE2A | O00408 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27424490 | 0.86 | SLC29A1 (0.57) | ADORA3SLC29A1 | |
| SCHEMBL27423891 | 0.84 | NT5E (0.50) | ADORA3NT5EPDE2ALMNATP53 | |
| SCHEMBL27428645 | 0.84 | ADORA3 (0.56) | ADORA3NT5EPDE2ALMNATP53 | |
| SCHEMBL27430559 | 0.79 | ADORA3 (0.49) | ADORA3SLC29A1 | |
| SCHEMBL27423523 | 0.77 | SLC29A1 (0.60) | ADORA3NT5ELMNATP53SLC29A1 | |
| SCHEMBL27428742 | 0.77 | SLC29A1 (0.56) | ADORA3SLC29A1 | |
| SCHEMBL27425390 | 0.76 | SLC29A1 (0.62) | ADORA3SLC29A1 | |
| SCHEMBL27425126 | 0.75 | SLC29A1 (0.59) | ADORA3SLC29A1 | |
| SCHEMBL27428046 | 0.75 | ADORA3 (0.52) | ADORA3SLC29A1 | |
| SCHEMBL27427947 | 0.75 | SLC29A1 (0.61) | ADORA3SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024134541-A1 | HETEROCYCLIC COMPOUNDS AS ENT INHIBITORS AND COMPOUNDS FOR USE IN THE TREATMENT OF CANCERS | iTeos Belgium SA (BE) | 2024-06-27 | — | — | WO | disclosed |