⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181307 | 0.72 | — | — | |
| SCHEMBL15733012 | 0.71 | — | — | |
| SCHEMBL10941207 | 0.70 | — | — | |
| Ammonia Solution, Strong SCHEMBL8747229 | 0.69 | RIPK1 (0.41) | — | |
| Hydrogen Peroxide SCHEMBL9456540 | 0.67 | RIPK1 (0.44) | — | |
| SCHEMBL20609991 | 0.67 | MEN1 (0.31) | — | |
| SCHEMBL28987495 | 0.67 | — | — | |
| SCHEMBL18881747 | 0.66 | MEN1 (0.33) | — | |
| SCHEMBL10661408 | 0.65 | MEN1 (0.30) | — | |
| SCHEMBL4543712 | 0.65 | RIPK1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024119049-A1 | COMPOSITIONS AND METHODS FOR PROTEIN INTERNALIZATION | LYTICA THERAPEUTICS, INC. (US) | 2024-06-06 | — | — | WO | disclosed |