SCHEMBL27424006

SCHEMBL27424006

CCOC(=O)c1cccc(C(=O)Oc2ccccc2)c1N

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.59
HSD17B10 Q99714 5/20 0.59
TSHR P16473 3/20 0.59
MAPT P10636 5/20 0.58
TDP1 Q9NUW8 2/20 0.51
KDM4E B2RXH2 2/20 0.51
HPGD P15428 6/20 0.51
SMN1; SMN2 Q16637 5/20 0.51
RAB9A P51151 4/20 0.51
ALOX15 P16050 3/20 0.51
GAA P10253 1/20 0.51
MAPK1 P28482 2/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
CASP3 P42574 1/20 0.49
SENP8 Q96LD8 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
SENP6 Q9GZR1 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9501331 0.89 TSHR (0.75) ALDH1A1HSD17B10TSHRMAPTTDP1
SCHEMBL27424975 0.87 TSHR (0.70) ALDH1A1HSD17B10TSHRMAPTKDM4E
SCHEMBL27428446 0.87 MAPT (0.65) ALDH1A1HSD17B10TSHRMAPTTDP1
SCHEMBL13816768 0.84 ALDH1A1 (0.62) ALDH1A1HSD17B10TSHRMAPTKDM4E
SCHEMBL2008036 0.83 MAPT (0.53) ALDH1A1HSD17B10TSHRMAPTTDP1
SCHEMBL28094803 0.83 MAPT (0.56) ALDH1A1HSD17B10MAPTTDP1KDM4E
SCHEMBL27426171 0.83 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRMAPTTDP1
SCHEMBL27424004 0.82 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRMAPTHPGD
SCHEMBL28845709 0.82 ALDH1A1 (0.59) ALDH1A1HSD17B10TSHRMAPTTDP1
SCHEMBL27424971 0.81 HSD17B10 (0.62) ALDH1A1HSD17B10TSHRMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1111152-C method for producing aromatic carbonates ASAHI CHEMICAL IND (JP) 2003-06-11 CN disclosed
CN-1265641-A method for producing aromatic carbonates ASAHI CHEMICAL IND (JP) 2000-09-06 CN disclosed