⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5827395 | 0.74 | — | — | |
| SCHEMBL505931 | 0.71 | — | — | |
| SCHEMBL3121774 | 0.71 | — | — | |
| SCHEMBL1920259 | 0.71 | — | — | |
| SCHEMBL1920338 | 0.71 | — | — | |
| SCHEMBL6358054 | 0.70 | LMNA (0.31) | — | |
| SCHEMBL9655443 | 0.69 | — | — | |
| SCHEMBL4926514 | 0.67 | MAPT (0.32) | — | |
| SCHEMBL16486907 | 0.67 | — | — | |
| SCHEMBL10619301 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107417608-A | A kind of synthetic method of Ciclopirox Olamine | 江西永通科技股份有限公司 | 2017-12-01 | — | — | CN | claimed |
| CN-104997780-B | A kind of Rosuvastatin calcium composition and its application in reducing blood lipid hypoglycemic medicament is prepared | 上海旭东海普药业有限公司 | 2018-03-23 | — | — | CN | disclosed |
| CN-104940193-B | A kind of reducing blood lipid hypoglycemic medicament composition and its application containing Simvastatin | 王加峰 | 2017-12-12 | — | — | CN | disclosed |
| CN-107417608-A | A kind of synthetic method of Ciclopirox Olamine | 江西永通科技股份有限公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-1109749-A | Methods for inhibiting uterine fibrosis | LILLY CO ELI (US) | 1995-10-11 | — | — | CN | disclosed |
| CN-1105853-A | Methods for inhibiting bone loss | LILLY CO ELI (US) | 1995-08-02 | — | — | CN | disclosed |