Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764084 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL7797419 | 0.77 | GSK3B (0.49) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL27456478 | 0.77 | GAA (0.50) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL7347272 | 0.76 | PLA2G10 (0.42) | ALDH1A1MAOAMAOB | |
| SCHEMBL2422131 | 0.74 | HSD17B10 (0.50) | ALDH1A1 | |
| SCHEMBL27424321 | 0.73 | KDM4E (0.55) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL17504448 | 0.72 | KDM4E (0.54) | ALDH1A1 | |
| SCHEMBL9693848 | 0.72 | HSD17B10 (0.48) | ALDH1A1 | |
| SCHEMBL11427988 | 0.72 | HSD17B10 (0.48) | ALDH1A1 | |
| SCHEMBL13887602 | 0.72 | MAOA (0.35) | SMN1; SMN2ALDH1A1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1109057-A | Imidazopyridazine | MERCK PATENT GMBH (DE) | 1995-09-27 | — | — | CN | disclosed |