Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.39 |
| ▸ | HTR2A | P28223 | 6/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27480381 | 0.85 | HTR2A (0.36) | TAAR1HTR2AHTR2CGAAMAPT | |
| SCHEMBL7684229 | 0.82 | TAAR1 (0.44) | TAAR1HTR2AGAAMAPTTSHR | |
| SCHEMBL28780524 | 0.79 | TAAR1 (0.40) | TAAR1HTR2AHTR2CGAAHTR2B | |
| SCHEMBL27764063 | 0.79 | TAAR1 (0.43) | TAAR1HTR2AHTR2CGAAMAPT | |
| SCHEMBL27426140 | 0.76 | TAAR1 (0.36) | TAAR1GAA | |
| SCHEMBL28164689 | 0.75 | KDM4E (0.34) | — | |
| SCHEMBL592705 | 0.74 | CYP3A4 (0.39) | MAPTTSHRCYP1A2 | |
| SCHEMBL7463224 | 0.74 | HTR2A (0.50) | HTR2A | |
| SCHEMBL2761914 | 0.74 | TAAR1 (0.56) | TAAR1HTR2AHTR2CGAAMAPT | |
| SCHEMBL1637863 | 0.71 | ACHE (0.39) | TAAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101696208-B | Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with a cyclic amino group as CRF antagonists | TAISHO PHARMACEUTICAL CO LTD | 2013-09-25 | — | — | CN | disclosed |
| CN-1107158-A | Polysubstituted 2-amino-thiazole derivatives | SANOFI ELF (FR) | 1995-08-23 | — | — | CN | disclosed |