Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | PRKCA | P17252 | 1/20 | 0.55 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.55 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | GMNN | O75496 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8585394 | 1.00 | MAPK1 (0.64) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL9615401 | 1.00 | MAPK1 (0.64) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL29407399 | 1.00 | MAPK1 (0.64) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL25703866 | 1.00 | MAPK1 (0.64) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL29516600 | 1.00 | MAPK1 (0.64) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL29672088 | 1.00 | MAPK1 (0.64) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL30577027 | 1.00 | MAPK1 (0.64) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL5145605 | 0.98 | MAPK1 (0.62) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL31399489 | 0.94 | MAPK1 (0.57) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL31399408 | 0.94 | MAPK1 (0.57) | MAPK1MAPTLMNAALDH1A1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12024484-B2 | Lipid formulations for gene editing | VERVE THERAPEUTICS, INC. (US) | 2024-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12024484-B2 | Lipid formulations for gene editing | LIPA, LIPC, ABHD16A | MAPK1 4761/4885MAPT 3608/4885LMNA 822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.