Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 9/20 | 0.59 |
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.59 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.55 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.48 |
| ▸ | LPAR6 | P43657 | 5/20 | 0.48 |
| ▸ | LPAR4 | Q99677 | 5/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18544636 | 0.93 | LPAR1 (0.58) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL18544676 | 0.93 | LPAR1 (0.58) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL17213446 | 0.91 | LPAR1 (0.60) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL16303701 | 0.89 | LPAR1 (0.62) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL15158747 | 0.89 | LPAR1 (0.62) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL19829619 | 0.89 | LPAR1 (0.62) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL14877975 | 0.89 | LPAR1 (0.62) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL13659941 | 0.89 | LPAR1 (0.62) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL26304918 | 0.87 | LPAR1 (0.55) | LPAR1LPAR3LPAR2 | |
| SCHEMBL7563995 | 0.87 | LPAR1 (0.68) | LPAR1LPAR3LPAR2LPAR5LPAR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12024484-B2 | Lipid formulations for gene editing | VERVE THERAPEUTICS, INC. (US) | 2024-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12024484-B2 | Lipid formulations for gene editing | LIPA, LIPC, ABHD16A | LPAR1 119/4885LPAR3 140/4885LPAR2 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.