Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | RARB | P10826 | 4/20 | 0.37 |
| ▸ | RARG | P13631 | 4/20 | 0.37 |
| ▸ | RARA | P10276 | 3/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.37 |
| ▸ | GOT1 | P17174 | 1/20 | 0.37 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.37 |
| ▸ | PTP4A3 | O75365 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7512464 | 0.84 | NR4A2 (0.53) | MEN1KMT2ARARBRARGRARA | |
| SCHEMBL7927701 | 0.81 | NR4A2 (0.45) | MEN1KMT2ARARBRARGRARA | |
| SCHEMBL7518648 | 0.77 | MEN1 (0.64) | MEN1KMT2ARARBRARGRARA | |
| SCHEMBL8457461 | 0.75 | RARB (0.48) | MEN1KMT2ARARBRARGRARA | |
| SCHEMBL7932567 | 0.75 | TRPV6 (0.43) | MEN1KMT2APTP4A3FAAHCNR2 | |
| SCHEMBL7517611 | 0.75 | MEN1 (0.53) | MEN1KMT2ARARBRARGRARA | |
| SCHEMBL8460810 | 0.74 | RARB (0.43) | MEN1KMT2ARARBRARGRARA | |
| SCHEMBL7926514 | 0.74 | RARB (0.54) | MEN1KMT2ARARBRARGRARA | |
| SCHEMBL8688173 | 0.73 | TRPV6 (0.41) | MEN1KMT2ARARBRARGRARA | |
| SCHEMBL8438827 | 0.73 | MEN1 (0.66) | MEN1KMT2ARARBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1104896-C | 'Gamma'-RAR antagonist ligand or 'alpha'-RAR agonist ligand as apoptosis inhibitor | GALDERMA RECH DERMATOLOGIQUE (FR) | 2003-04-09 | — | — | CN | claimed |
| CN-1203529-A | RAR-gamma antagonist ligands or RAR-alpha agonist ligands as apoptosis inhibitors | CIRD GALDERMA (FR) | 1998-12-30 | — | — | CN | claimed |
| CN-1104896-C | 'Gamma'-RAR antagonist ligand or 'alpha'-RAR agonist ligand as apoptosis inhibitor | GALDERMA RECH DERMATOLOGIQUE (FR) | 2003-04-09 | — | — | CN | disclosed |
| CN-1203529-A | RAR-gamma antagonist ligands or RAR-alpha agonist ligands as apoptosis inhibitors | CIRD GALDERMA (FR) | 1998-12-30 | — | — | CN | disclosed |