Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 5/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26999635 | 0.94 | SPHK1 (0.39) | SPHK1LSSBCHE | |
| SCHEMBL23219669 | 0.94 | SPHK1 (0.41) | SPHK1GBA1 | |
| SCHEMBL19286118 | 0.87 | SPHK1 (0.43) | SPHK1LSS | |
| SCHEMBL25748478 | 0.87 | SPHK1 (0.43) | SPHK1LSS | |
| SCHEMBL24040186 | 0.87 | SPHK1 (0.43) | SPHK1LSS | |
| SCHEMBL19388485 | 0.85 | SPHK1 (0.41) | SPHK1 | |
| SCHEMBL4276675 | 0.82 | FDPS (0.36) | — | |
| SCHEMBL4275008 | 0.82 | FDPS (0.36) | — | |
| SCHEMBL22121579 | 0.82 | FDPS (0.36) | SPHK1 | |
| SCHEMBL27942598 | 0.82 | FDPS (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217972-A1 | GLUTARIMIDE-CONTAINING PAN-KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF | TIGER BIOTHERAPEUTICS INC. | 2024-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240217972-A1 | GLUTARIMIDE-CONTAINING PAN-KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF | KRAS, VHL, HRAS | SPHK1 3487/4885LSS 4643/4885BCHE 3222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.