Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 5/20 | 0.39 |
| ▸ | THRA | P10827 | 4/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25962151 | 1.00 | DNM1 (0.44) | DNM1EPHX2THRBTHRAKDM5A | |
| SCHEMBL25961989 | 0.92 | DNM1 (0.47) | DNM1EPHX2KDM5AKDM4CPHF8 | |
| SCHEMBL22208603 | 0.92 | DNM1 (0.47) | DNM1EPHX2KDM5AKDM4CPHF8 | |
| SCHEMBL25964213 | 0.92 | DNM1 (0.47) | DNM1EPHX2KDM5AKDM4CPHF8 | |
| SCHEMBL31271906 | 0.92 | EPHX2 (0.43) | DNM1EPHX2THRBTHRAKDM5A | |
| SCHEMBL31272292 | 0.90 | EPHX2 (0.42) | DNM1EPHX2THRBTHRAKDM5A | |
| SCHEMBL24495926 | 0.89 | DNM1 (0.46) | DNM1EPHX2KDM5AKDM4CPHF8 | |
| SCHEMBL25962459 | 0.89 | DNM1 (0.46) | DNM1EPHX2KDM5AKDM4CPHF8 | |
| SCHEMBL24016802 | 0.89 | DNM1 (0.46) | DNM1EPHX2KDM5AKDM4CPHF8 | |
| SCHEMBL28660292 | 0.88 | DNM1 (0.43) | DNM1EPHX2KDM5AKDM4CPHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3908568-B1 | LIPIDS FOR LIPID NANOPARTICLE DELIVERY OF ACTIVE AGENTS | ACUITAS THERAPEUTICS INC (CA) | 2024-06-26 | — | — | EP | disclosed |