SCHEMBL2742816

SCHEMBL2742816

O=C(c1ccc(Nc2ccccc2)cc1)c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.95

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK13 O15264 2/20 0.95
MAPK12 P53778 2/20 0.95
MAPK11 Q15759 2/20 0.95
MAPK14 Q16539 2/20 0.95
ALDH1A1 P00352 8/20 0.62
L3MBTL1 Q9Y468 2/20 0.62
HSD17B10 Q99714 2/20 0.62
MAPK1 P28482 2/20 0.62
ALOX15 P16050 1/20 0.62
TSHR P16473 1/20 0.62
ALOX12 P18054 1/20 0.62
PTGS1 P23219 1/20 0.62
SLC6A2 P23975 1/20 0.62
PTGS2 P35354 1/20 0.62
HTR2B P41595 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
CASP3 P42574 1/20 0.61
SENP7 Q9BQF6 1/20 0.61
MEN1 O00255 5/20 0.61
KMT2A Q03164 5/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5154269 0.98 MAPK13 (1.00) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL29196087 0.95 MAPK13 (0.95) MAPK13MAPK12MAPK11MAPK14ALDH1A1
Benzophenone SCHEMBL329500 0.93 MAPK13 (0.91) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL9479471 0.86 MAPK13 (0.72) MAPK13MAPK12MAPK11MAPK14ALDH1A1
4-Phenylamino Benzoic Acid SCHEMBL70190 0.86 MAPK13 (0.72) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL2791237 0.86 MAPK13 (0.78) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL2789324 0.86 MAPK13 (0.78) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL14571018 0.86 MAPK13 (0.78) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL29042747 0.84 MAPK13 (0.76) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL14982062 0.83 MAPK13 (0.74) MAPK13MAPK12MAPK11MAPK14ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation FUJIFILM CORPORATION (JP) 2019-07-16 US disclosed
US-9535347-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-01-03 US disclosed
US-9459542-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and gallium phthalocyanine crystal CANON KABUSHIKI KAISHA (JP) 2016-10-04 US disclosed
US-9459542-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and gallium phthalocyanine crystal CANON KABUSHIKI KAISHA (JP) 2016-10-04 US disclosed
US-9348242-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-05-24 US disclosed
US-9348242-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-05-24 US disclosed
US-9223233-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-12-29 US disclosed
US-9223233-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-12-29 US disclosed
US-9068083-B2 Method of producing gallium phthalocyanine crystal and method of producing electrophotographic photosensitive member using the method of producing gallium phthalocyanine crystal CANON KABUSHIKI KAISHA (JP) 2015-06-30 US disclosed
US-9068083-B2 Method of producing gallium phthalocyanine crystal and method of producing electrophotographic photosensitive member using the method of producing gallium phthalocyanine crystal CANON KABUSHIKI KAISHA (JP) 2015-06-30 US disclosed
US-20140141362-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2014-05-22 US disclosed
US-20140141362-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2014-05-22 US disclosed
US-20130137023-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2013-05-30 US disclosed
US-20130137023-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2013-05-30 US disclosed
US-20130137032-A1 METHOD OF PRODUCING GALLIUM PHTHALOCYANINE CRYSTAL AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER USING THE METHOD OF PRODUCING GALLIUM PHTHALOCYANINE CRYSTAL CANON KABUSHIKI KAISHA (JP) 2013-05-30 US disclosed
US-20130137032-A1 METHOD OF PRODUCING GALLIUM PHTHALOCYANINE CRYSTAL AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER USING THE METHOD OF PRODUCING GALLIUM PHTHALOCYANINE CRYSTAL CANON KABUSHIKI KAISHA (JP) 2013-05-30 US disclosed
US-8415078-B2 Electrophotographic photosensitive member, process electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2013-04-09 US disclosed
US-8415078-B2 Electrophotographic photosensitive member, process electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2013-04-09 US disclosed
US-20120003576-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2012-01-05 US disclosed
US-20120003576-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2012-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation O60361, WDR12, SEM1 MAPK13 1639/4885MAPK12 833/4885MAPK11 231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.