4-Phenylamino Benzoic Acid

4-Phenylamino Benzoic Acid

SCHEMBL70190

O=C(O)c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK13 O15264 1/20 0.72
MAPK12 P53778 1/20 0.72
MAPK11 Q15759 1/20 0.72
MAPK14 Q16539 1/20 0.72
ALDH1A1 P00352 3/20 0.64
HSD17B10 Q99714 3/20 0.62
TSHR P16473 3/20 0.62
ALOX15 P16050 1/20 0.62
ALOX12 P18054 1/20 0.62
PTGS1 P23219 1/20 0.62
SLC6A2 P23975 1/20 0.62
MAPK1 P28482 1/20 0.62
PTGS2 P35354 1/20 0.62
HTR2B P41595 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
CASP3 P42574 1/20 0.61
SENP7 Q9BQF6 1/20 0.61
MAPT P10636 3/20 0.61
GAA P10253 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9479471 1.00 MAPK13 (0.72) MAPK13MAPK12MAPK11MAPK14ALDH1A1
Diphenylamine SCHEMBL9331071 0.93 TSHR (0.70) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL251773 0.93 TSHR (0.67) MAPK13MAPK12MAPK11MAPK14ALDH1A1
Diphenylamine SCHEMBL28581119 0.87 SMN1; SMN2 (0.68) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL2742816 0.86 MAPK13 (0.95) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL4569980 0.86 RHOA (0.72) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL2127845 0.84 TYR (0.73) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL5154269 0.84 MAPK13 (1.00) MAPK13MAPK12MAPK11MAPK14ALDH1A1
Diphenylamine SCHEMBL28427475 0.83 ALDH1A1 (0.64) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL7524753 0.82 ALDH1A1 (0.69) MAPK13MAPK12MAPK11MAPK14ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117599758-A Preparation method of adsorbent for efficiently adsorbing aflatoxin M1 in goat milk 陕西师范大学 2024-02-27 CN claimed
CN-116813938-A Conjugated small molecule modified hydrogel and preparation method thereof 金陵科技学院 2023-09-29 CN claimed
US-20220227999-A1 UNSYMMETRICAL SQUARAINE DYES AND APLLICATIONS THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2022-07-21 US claimed
US-9815067-B2 Electret webs with charge-enhancing additives 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-11-14 US claimed
EP-2986354-B1 ELECTRET WEBS WITH CHARGE-ENHANCING ADDITIVES 3M INNOVATIVE PROPERTIES CO (US) 2017-06-14 EP claimed
US-20160067717-A1 ELECTRET WEBS WITH CHARGE-ENHANCING ADDITIVES 3M INNOVATIVE PROPERTIES COMPANY 2016-03-10 US claimed
EP-2986354-A2 ELECTRET WEBS WITH CHARGE-ENHANCING ADDITIVES 3M Innovative Properties Company (US) 2016-02-24 EP claimed
WO-2014172308-A2 ELECTRET WEBS WITH CHARGE-ENHANCING ADDITIVES 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-10-23 WO claimed
EP-0623635-B1 Amine-functionalized polyester GEN ELECTRIC (US) 2003-02-19 EP claimed
EP-0443742-B1 Presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 1997-10-01 EP claimed
US-5476754-A Presensitized; hydrophilic surface on substrate; light sensitive layer containing alkaline water-soluble photocrosslinkable copolycondensed diazo resin FUJI PHOTO FILM CO., LTD. (JP) 1995-12-19 US claimed
EP-0443742-A2 Presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1991-08-28 EP claimed
EP-0415422-A2 Method for forming images FUJI PHOTO FILM CO., LTD. (JP) 1991-03-06 EP claimed
US-20250179046-A1 SEROTONIN 5-HT2B INHIBITORY COMPOUNDS ZOETIS SERVICES LLC 2025-06-05 US disclosed
WO-2025104079-A1 SALICYLIC ACID AND PICOLINIC ACID DERIVATIVES AS INHIBITORS OF ENERGY COUPLING FACTOR (ECF) TRANSPORTERS FOR THE TREATMENT OF BACTERIAL INFECTIONS Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2025-05-22 WO disclosed
WO-2025086591-A1 ROTIGOTINE PRODRUG DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 烟台药物研究所 2025-05-01 WO disclosed
EP-0379055-A2 Mesogenic advanced epoxy compounds THE DOW CHEMICAL COMPANY (US) 1990-07-25 EP disclosed
US-4325884-A Method for the preparation of bis(ρ-aminobenzoato) cobalt THE FIRESTONE TIRE & RUBBER COMPANY (US) 1982-04-20 US disclosed
US-4207330-A Method for treating hyperglycemia in mammals using arylamino benzoic acids THE DOW CHEMICAL COMPANY (US) 1980-06-10 US disclosed
US-4143151-A METHOD FOR TREATING HYPERGLYCEMIA IN MAMMALS USING ARYLAMINO BENZOIC ACIDS THE DOW CHEMICAL COMPANY (US) 1979-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179046-A1 SEROTONIN 5-HT2B INHIBITORY COMPOUNDS HTR2B, HTR1B, HTR5A MAPK13 2278/4885MAPK12 2747/4885MAPK11 1729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.