Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094750 | 0.88 | PDPK1 (0.42) | PDPK1LOXL2ADRB2CYP2A6TLR8 | |
| SCHEMBL8499706 | 0.72 | PDE10A (0.44) | PDPK1LOXL2ADRB2CYP2A6TLR8 | |
| SCHEMBL8088436 | 0.72 | PDE10A (0.44) | PDPK1LOXL2ADRB2CYP2A6TLR8 | |
| SCHEMBL27947333 | 0.70 | FGFR1 (0.43) | QPCTCHEK1 | |
| SCHEMBL722198 | 0.70 | PDPK1 (0.77) | PDPK1LOXL2ADRB2CYP2A6PTGDR2 | |
| SCHEMBL27947326 | 0.69 | MAP4K4 (0.39) | PDPK1QPCTCHEK1CHEK2 | |
| SCHEMBL13142475 | 0.69 | PDPK1 (0.57) | PDPK1LOXL2ADRB2CYP2A6PTGDR2 | |
| SCHEMBL28151600 | 0.69 | PDPK1 (0.44) | PDPK1LOXL2ADRB2CYP2A6TLR8 | |
| SCHEMBL26259866 | 0.68 | PDPK1 (0.55) | PDPK1LOXL2ADRB2CYP2A6TLR8 | |
| SCHEMBL15805858 | 0.67 | PDPK1 (0.72) | PDPK1LOXL2ADRB2CYP2A6PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1105720-C | Imidazopyridazines compound | AOTANNA MEDICINE AG (DE) | 2003-04-16 | — | — | CN | disclosed |
| CN-1246120-A | Imidazopyridazines compound | BYK GULDEN LOMBERG CHEM FAB (DE) | 2000-03-01 | — | — | CN | disclosed |