Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 9/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19032775 | 0.83 | CFTR (0.72) | CFTRMEN1KMT2ARAB9AMAPT | |
| SCHEMBL19046548 | 0.83 | CFTR (0.85) | CFTRMEN1KMT2ARAB9AMAPT | |
| SCHEMBL19046547 | 0.81 | CFTR (0.69) | CFTRMEN1KMT2ARAB9AMAPT | |
| SCHEMBL24363056 | 0.77 | CFTR (0.72) | CFTRMEN1KMT2ARAB9AMAPT | |
| SCHEMBL19448876 | 0.76 | MEN1 (0.72) | CFTRMEN1KMT2ARAB9AMAPT | |
| SCHEMBL19032803 | 0.74 | CFTR (0.72) | CFTRMEN1KMT2ARAB9AMAPT | |
| SCHEMBL19032095 | 0.74 | CFTR (1.00) | CFTR | |
| SCHEMBL29478065 | 0.74 | CFTR (1.00) | CFTR | |
| SCHEMBL19032864 | 0.74 | CFTR (0.82) | CFTRMEN1KMT2ARAB9AMAPT | |
| SCHEMBL19032706 | 0.73 | CFTR (0.80) | CFTRMEN1KMT2AMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4071140-B1 | CFTR REGULATORS AND METHODS OF USE THEREOF | UNIV CALIFORNIA (US) | 2024-07-03 | — | — | EP | disclosed |