⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24297657 | 0.67 | — | — | |
| SCHEMBL28184284 | 0.67 | — | — | |
| SCHEMBL24604205 | 0.62 | — | — | |
| SCHEMBL905276 | 0.57 | — | — | |
| SCHEMBL27797982 | 0.57 | — | — | |
| SCHEMBL9263290 | 0.57 | — | — | |
| SCHEMBL910902 | 0.53 | — | — | |
| SCHEMBL823128 | 0.51 | — | — | |
| SCHEMBL23392479 | 0.48 | — | — | |
| SCHEMBL843718 | 0.47 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104395301-B | Bicyclic thiophene base amide compound | 霍夫曼-拉罗奇有限公司 | 2017-07-28 | — | — | CN | disclosed |
| CN-105037323-A | Thiochromene derivatives as HIF hydroxylase inhibitors | FIBROGEN INC | 2015-11-11 | — | — | CN | disclosed |
| CN-102272117-B | Benzothiopyran derivatives as HIF hydroxylase inhibitors | FIBROGEN INC | 2015-06-17 | — | — | CN | disclosed |
| CN-104395301-A | New bicyclic thiophenylamide compounds | HOFFMANN LA ROCHE | 2015-03-04 | — | — | CN | disclosed |
| CN-102272117-A | Benzothiopyran derivatives as HIF hydroxylase inhibitors | — | 2011-12-07 | — | — | CN | disclosed |
| CN-1751042-B | Pyrazolo[3,4-b]pyridine compounds, and their use as phosphodiesterase inhibitors | GLAXO GROUP LTD | 2011-02-23 | — | — | CN | disclosed |
| CN-1106399-A | Cyclic aldehyde ethers, their preparation and their use as crop protection agents | BASF AG (DE) | 1995-08-09 | — | — | CN | disclosed |