Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 8/20 | 0.37 |
| ▸ | CCND1 | P24385 | 8/20 | 0.37 |
| ▸ | CCND2 | P30279 | 8/20 | 0.37 |
| ▸ | CCND3 | P30281 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13242252 | 0.78 | PDE4A (0.37) | ALDH1A1LMNAMAPK1GSK3BADORA3 | |
| SCHEMBL761973 | 0.78 | CDK4 (0.38) | CDK4CCND1CCND2CCND3ALDH1A1 | |
| SCHEMBL28136429 | 0.76 | CDK4 (0.37) | CDK4CCND1CCND2CCND3ALDH1A1 | |
| SCHEMBL761369 | 0.76 | CDK4 (0.41) | CDK4CCND1CCND2CCND3ALDH1A1 | |
| SCHEMBL27480564 | 0.73 | CDK4 (0.36) | CDK4CCND1CCND2CCND3ALDH1A1 | |
| SCHEMBL761987 | 0.71 | KDM4E (0.49) | CDK4CCND1CCND2CCND3ALDH1A1 | |
| SCHEMBL1483873 | 0.68 | SMN1; SMN2 (0.41) | ALDH1A1LMNAHPGDHSD17B10GSK3B | |
| SCHEMBL27396922 | 0.68 | BTK (0.38) | CDK4CCND1CCND2CCND3ALDH1A1 | |
| SCHEMBL9378857 | 0.67 | CDK4 (0.52) | CDK4CCND1CCND2CCND3ALDH1A1 | |
| SCHEMBL19862684 | 0.65 | POLB (0.38) | ALDH1A1KDM4ELMNAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102216279-A | Phenyl pyrimidone compounds, pharmaceutical compositions, preparation methods and uses thereof | TOPHARMAN SHANGHAI CO LTD | 2011-10-12 | — | — | CN | claimed |
| CN-102216279-A | Phenyl pyrimidone compounds, pharmaceutical compositions, preparation methods and uses thereof | TOPHARMAN SHANGHAI CO LTD | 2011-10-12 | — | — | CN | disclosed |
| CN-1109879-A | 2-arylpyrimidines and herbicidal use thereof | ROHM & HAAS (US) | 1995-10-11 | — | — | CN | disclosed |