Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 14/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19764716 | 0.75 | LMNA (0.93) | NPSR1LMNAKMT2AMEN1USP2 | |
| SCHEMBL8302217 | 0.75 | PDE5A (0.59) | NPSR1LMNAKMT2AMEN1USP2 | |
| SCHEMBL20957843 | 0.73 | NPSR1 (0.54) | NPSR1LMNAKMT2AMEN1USP2 | |
| SCHEMBL15289603 | 0.72 | LMNA (0.60) | NPSR1LMNAKMT2AMEN1USP2 | |
| SCHEMBL8537006 | 0.71 | TSHR (1.00) | NPSR1LMNAKMT2AMEN1USP2 | |
| SCHEMBL543684 | 0.70 | LMNA (0.49) | NPSR1LMNAKMT2AMEN1USP2 | |
| SCHEMBL14342691 | 0.70 | LMNA (0.49) | NPSR1LMNAKMT2AMEN1USP2 | |
| SCHEMBL27699163 | 0.70 | MEN1 (0.51) | NPSR1LMNAKMT2AMEN1USP2 | |
| SCHEMBL27427122 | 0.69 | TSHR (0.48) | NPSR1LMNAKMT2AMEN1USP2 | |
| SCHEMBL715587 | 0.68 | NPSR1 (0.47) | NPSR1LMNAKMT2AMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1109055-A | 4-aminopyrimidine derivatives | ONO PHARMACEUTICAL CO (JP) | 1995-09-27 | — | — | CN | claimed |
| CN-1109055-A | 4-aminopyrimidine derivatives | ONO PHARMACEUTICAL CO (JP) | 1995-09-27 | — | — | CN | disclosed |