⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27254599 | 1.00 | — | — | |
| SCHEMBL16543649 | 0.84 | — | — | |
| SCHEMBL19805230 | 0.84 | — | — | |
| SCHEMBL18119006 | 0.83 | — | — | |
| SCHEMBL2754696 | 0.83 | — | — | |
| SCHEMBL20381169 | 0.83 | — | — | |
| SCHEMBL25797559 | 0.82 | — | — | |
| SCHEMBL18233152 | 0.79 | — | — | |
| SCHEMBL25797561 | 0.77 | ACHE (0.37) | — | |
| SCHEMBL13171605 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180021449-A1 | ANTISENSE CONJUGATES FOR DECREASING EXPRESSION OF DMPK | VALERION THERAPEUTICS, LLC | 2018-01-25 | — | — | US | disclosed |
| EP-1747024-B1 | DNA VIRUS MICRORNA AND METHODS FOR INHIBITING SAME | UNIV ROCKEFELLER (US) | 2017-07-12 | — | — | EP | disclosed |
| US-20140065223-A1 | PERFLUORINATED COMPOUNDS FOR THE NON-VIRAL TRANSFER OF NUCLEIC ACIDS | Libera-Koerner, Jeanette (DE) | 2014-03-06 | — | — | US | disclosed |
| US-20120115220-A1 | Anti-MicroRNA Oligonucleotide Molecules | ROCKEFELLER UNIVERSITY (US) | 2012-05-10 | — | — | US | disclosed |
| EP-1750771-B1 | PANCREATIC ISLET MICRORNA AND METHODS FOR INHIBITING SAME | UNIV ROCKEFELLER (US) | 2012-05-09 | — | — | EP | disclosed |
| US-8088902-B2 | Isolated nucleic acid molecule comprising the sequence of a DNA virus microRNA; Epstein barr virus; inhibiting microRNP activity in a cell | THE ROCKEFELLER UNIVERSITY (US) | 2012-01-03 | — | — | US | disclosed |
| US-20110165669-A1 | Anti-MicroRNA Oligonucleotide Molecules | ROCKEFELLER UNIVERSITY (US) | 2011-07-07 | — | — | US | disclosed |
| US-7943756-B2 | Anti-microRNA oligonucleotide molecules | ROCKEFELLER UNIVERSITY (US) | 2011-05-17 | — | — | US | disclosed |
| US-20100286385-A1 | Anti-MicroRNA Oligonucleotide Molecules | ROCKEFELLER UNIVERSITY (US) | 2010-11-11 | — | — | US | disclosed |
| US-7772389-B2 | Inhibiting ribonucleoprotein particles (miRNPs) activity in a cell | ROCKEFELLER UNIVERSITY (US) | 2010-08-10 | — | — | US | disclosed |
| US-7365058-B2 | MicroRNA and methods for inhibiting same | THE ROCKEFELLER UNIVERSITY (US) | 2008-04-29 | — | — | US | disclosed |
| US-20070287179-A1 | Inhibiting ribonucleoprotein particles (miRNPs) activity in a cell | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-12-13 | — | — | US | disclosed |