Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | ENPP3 | O14638 | 5/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 5/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11313379 | 0.94 | TDP1 (0.61) | TDP1CA2CA1CA9MAPT | |
| SCHEMBL8599495 | 0.89 | TDP1 (0.54) | TDP1CA2CA1CA9MAPT | |
| SCHEMBL8602840 | 0.89 | TDP1 (0.54) | TDP1CA2CA1CA9MAPT | |
| SCHEMBL7981247 | 0.85 | TDP1 (0.73) | TDP1CA2CA1CA9MAPT | |
| SCHEMBL19146 | 0.85 | TDP1 (0.73) | TDP1CA2CA1CA9MAPT | |
| SCHEMBL9309112 | 0.83 | TDP1 (0.71) | TDP1CA2CA1CA9MAPT | |
| Ammonia Solution, Strong SCHEMBL8363523 | 0.83 | TDP1 (0.70) | TDP1CA2CA1CA9MAPT | |
| SCHEMBL28934632 | 0.83 | TDP1 (0.70) | TDP1CA2CA1CA9MAPT | |
| SCHEMBL1674227 | 0.83 | TDP1 (0.70) | TDP1CA2CA1CA9MAPT | |
| SCHEMBL2058543 | 0.82 | TDP1 (0.69) | TDP1CA2CA1CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115484950-A | Agents for use in the treatment of tissue damage | UCL商业有限责任公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-1086700-C | Benzothiophene compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2002-06-26 | — | — | CN | disclosed |
| CN-1159448-A | Benzothiophene compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 1997-09-17 | — | — | CN | disclosed |