Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 8/20 | 0.54 |
| ▸ | CA12 | O43570 | 6/20 | 0.54 |
| ▸ | CA9 | Q16790 | 4/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.49 |
| ▸ | PARL | Q9H300 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602840 | 1.00 | TDP1 (0.54) | TDP1CA2CA12CA9CA1 | |
| SCHEMBL11313379 | 0.95 | TDP1 (0.61) | TDP1CA2CA12CA9CA1 | |
| SCHEMBL27428841 | 0.89 | TDP1 (0.67) | TDP1CA2CA12CA9CA1 | |
| SCHEMBL10950314 | 0.87 | TDP1 (0.58) | TDP1CA2CA12CA9CA1 | |
| SCHEMBL8442031 | 0.87 | TDP1 (0.58) | TDP1CA2CA12CA9CA1 | |
| SCHEMBL2058543 | 0.87 | TDP1 (0.69) | TDP1CA2CA12CA9CA1 | |
| SCHEMBL17287705 | 0.85 | CA2 (0.57) | CA2CA12CA9CA1ALDH1A1 | |
| SCHEMBL24604538 | 0.83 | CA2 (0.62) | TDP1CA2CA12CA9CA1 | |
| SCHEMBL6937794 | 0.83 | CA2 (0.62) | TDP1CA2CA12CA9CA1 | |
| SCHEMBL8600833 | 0.83 | TDP1 (0.80) | TDP1CA2CA12CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508424-B1 | Method for preparing sulfones | SANKO KAIHATSU KAGAKU KENK (JP) | 1998-02-04 | — | — | EP | disclosed |
| US-5248828-A | Method for preparing sulfones | SANKO KAIHATSU KAGAKU KENKYUSHO (JP) | 1993-09-28 | — | — | US | disclosed |
| US-5235084-A | METHOD FOR PREPARING SULFONES | SANKO KAIHATSU KAGAKU KENKYUSHO (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0508424-A2 | Method for preparing sulfones | Sanko Kaihatsu Kagaku Kenkyusho (JP) | 1992-10-14 | — | — | EP | disclosed |