Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 12/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 12/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 12/20 | 0.33 |
| ▸ | DPP4 | P27487 | 6/20 | 0.33 |
| ▸ | CHRNB3 | Q05901 | 4/20 | 0.33 |
| ▸ | CHRNA6 | Q15825 | 4/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 8/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 8/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20498553 | 0.83 | DPP4 (0.33) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL22191115 | 0.83 | DPP4 (0.33) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL9932814 | 0.83 | DPP4 (0.33) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL18956836 | 0.83 | DPP4 (0.33) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL18956916 | 0.83 | DPP4 (0.33) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL23162418 | 0.83 | DPP4 (0.33) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL20577099 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL22190933 | 0.82 | DPP4 (0.33) | DPP4DPP7DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL29212136 | 0.82 | DPP4 (0.33) | DPP4DPP7DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL29212135 | 0.82 | DPP4 (0.33) | DPP4DPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208923-A1 | SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION | JNANA THERAPEUTICS INC. | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208923-A1 | SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION | SLC18A2, SLC6A19, SLC1A1 | CHRNB2 752/4885CHRNA3 989/4885CHRNA4 1380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.