Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | ADK | P55263 | 1/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 8/20 | 0.44 |
| ▸ | RNMT | O43148 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27431352 | 0.83 | ADORA3 (0.54) | ADORA3SLC29A1ADORA1 | |
| SCHEMBL27424596 | 0.82 | SLC29A1 (0.52) | ADORA3ADKSLC29A1RNMTADORA1 | |
| SCHEMBL27431030 | 0.81 | SLC29A1 (0.60) | ADORA3SLC29A1ADORA1 | |
| SCHEMBL27428046 | 0.81 | ADORA3 (0.52) | ADORA3SLC29A1ADORA1 | |
| SCHEMBL27428044 | 0.80 | ADORA3 (0.47) | ADORA3ADKSLC29A1RNMTADORA1 | |
| SCHEMBL27434586 | 0.76 | SLC29A1 (0.48) | ADORA3ADKSLC29A1ADORA1 | |
| SCHEMBL27436134 | 0.74 | SLC29A1 (0.56) | ADORA3ADKSLC29A1 | |
| SCHEMBL27434287 | 0.73 | ADORA3 (0.51) | ADORA3ADKSLC29A1ADORA1 | |
| SCHEMBL27431103 | 0.72 | ADORA3 (0.53) | ADORA3SLC29A1 | |
| SCHEMBL27426410 | 0.71 | SLC29A1 (0.56) | ADORA3SLC29A1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024134541-A1 | HETEROCYCLIC COMPOUNDS AS ENT INHIBITORS AND COMPOUNDS FOR USE IN THE TREATMENT OF CANCERS | iTeos Belgium SA (BE) | 2024-06-27 | — | — | WO | disclosed |