Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.64 |
| ▸ | HTR2A | P28223 | 2/20 | 0.64 |
| ▸ | SRC | P12931 | 3/20 | 0.56 |
| ▸ | BRD4 | O60885 | 2/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.52 |
| ▸ | CCNK | O75909 | 1/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | CCND3 | P30281 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.50 |
| ▸ | GALR2 | O43603 | 1/20 | 0.48 |
| ▸ | GALR1 | P47211 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27248330 | 0.86 | L3MBTL1 (0.58) | HTR2CHTR2ASRCCCNKCCND3 | |
| SCHEMBL27248319 | 0.85 | HRH4 (0.46) | HTR2CHTR2ABRD4CCND3HRH4 | |
| SCHEMBL27429695 | 0.85 | HRH4 (0.49) | HTR2CHTR2ACCNA2CDK2SMN1; SMN2 | |
| SCHEMBL27430722 | 0.82 | HTR2C (0.44) | HTR2CHTR2ASRCSMN1; SMN2HRH4 | |
| SCHEMBL27429484 | 0.82 | BCL6 (0.66) | BRD4GRM4HRH4 | |
| SCHEMBL27248311 | 0.81 | HPGD (0.58) | HTR2CHTR2AALDH1A1HRH4 | |
| SCHEMBL27429988 | 0.80 | HTR2C (0.61) | HTR2CHTR2AHRH4 | |
| SCHEMBL30879557 | 0.79 | HTR2C (0.42) | HTR2CHTR2ASRCHRH4 | |
| SCHEMBL27430034 | 0.79 | HTR2C (0.48) | HTR2CHTR2ACCNKCCND3CDK9 | |
| SCHEMBL27248392 | 0.79 | HPGD (0.50) | HTR2CHTR2ABRD4CDK9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118607-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | CHDI FOUNDATION, INC. (US) | 2024-06-06 | — | — | WO | disclosed |