⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16089 | 0.76 | — | — | |
| SCHEMBL2554446 | 0.76 | — | — | |
| SCHEMBL1669222 | 0.73 | — | — | |
| SCHEMBL1696771 | 0.73 | TSHR (0.45) | — | |
| SCHEMBL14994705 | 0.72 | — | — | |
| Water SCHEMBL29008220 | 0.69 | TSHR (0.39) | — | |
| SCHEMBL7654376 | 0.69 | — | — | |
| SCHEMBL17214811 | 0.69 | — | — | |
| Itaconic Anhydride SCHEMBL25233 | 0.69 | — | — | |
| SCHEMBL322940 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117843633-A | Sulfoximine compounds, pharmaceutical compositions and uses thereof | 上海海和药物研究开发股份有限公司 | 2024-04-09 | — | — | CN | disclosed |
| US-8088794-B2 | Substituted amide derivatives and methods of use | AMGEN INC. (US) | 2012-01-03 | — | — | US | disclosed |
| US-20110118252-A1 | SUBSTITUTED AMIDE DERIVATIVES AND METHODS OF USE | AMGEN INC. (US) | 2011-05-19 | — | — | US | disclosed |
| EP-2113510-A1 | Pepstatin A derivatives | Freie Universität Berlin (DE) | 2009-11-04 | — | — | EP | disclosed |
| US-20080200458-A1 | Methods and compositions for the treatment of body composition disorders | LEXICON PHARMACEUTICALS, INC. | 2008-08-21 | — | — | US | disclosed |