Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 13/20 | 0.53 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 5/20 | 0.52 |
| ▸ | MMP3 | P08254 | 4/20 | 0.52 |
| ▸ | MMP9 | P14780 | 11/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.50 |
| ▸ | MMP8 | P22894 | 3/20 | 0.49 |
| ▸ | MMP12 | P39900 | 2/20 | 0.49 |
| ▸ | MMP14 | P50281 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5875639 | 0.92 | MMP2 (0.60) | MMP2ADAMTS5MMP13MMP3MMP9 | |
| SCHEMBL8839754 | 0.92 | MMP2 (0.60) | MMP2ADAMTS5MMP13MMP3MMP9 | |
| SCHEMBL27415617 | 0.88 | MMP2 (0.52) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL27505498 | 0.86 | MMP2 (0.58) | MMP2ADAMTS5MMP13MMP3MMP9 | |
| SCHEMBL27505497 | 0.86 | MMP2 (0.58) | MMP2ADAMTS5MMP13MMP3MMP9 | |
| SCHEMBL8839291 | 0.84 | MMP2 (0.57) | MMP2ADAMTS5MMP13MMP3MMP9 | |
| SCHEMBL8839572 | 0.84 | MMP2 (0.57) | MMP2ADAMTS5MMP13MMP3MMP9 | |
| SCHEMBL8839281 | 0.84 | MMP2 (0.57) | MMP2ADAMTS5MMP13MMP3MMP9 | |
| SCHEMBL8839750 | 0.82 | MMP2 (0.58) | MMP2ADAMTS5MMP13MMP3MMP9 | |
| SCHEMBL8839753 | 0.82 | MMP2 (0.58) | MMP2ADAMTS5MMP13MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1249743-A | Arylsulfonylamino hydroxamic acid derivs | PFIZER PROD INC (US) | 2000-04-05 | — | — | CN | claimed |
| CN-1113862-C | Arylsulfonylamino hydroxamic acid derivs | PFIZER PROD INC (US) | 2003-07-09 | — | — | CN | disclosed |
| CN-1249743-A | Arylsulfonylamino hydroxamic acid derivs | PFIZER PROD INC (US) | 2000-04-05 | — | — | CN | disclosed |