Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 6/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27433002 | 0.92 | SLC29A1 (0.75) | SLC29A1ADORA3CYP3A4TSHRNFKB1 | |
| SCHEMBL27429819 | 0.89 | SLC29A1 (0.71) | SLC29A1ADORA3CYP3A4TSHRNFKB1 | |
| SCHEMBL27437734 | 0.86 | ADORA3 (0.76) | SLC29A1ADORA3TSHR | |
| SCHEMBL27434733 | 0.84 | SLC29A1 (0.71) | SLC29A1ADORA3CYP3A4TSHRNFKB1 | |
| SCHEMBL27432338 | 0.83 | SLC29A1 (0.70) | SLC29A1ADORA3 | |
| SCHEMBL27429365 | 0.82 | SLC29A1 (0.69) | SLC29A1ADORA3 | |
| SCHEMBL27435641 | 0.82 | SLC29A1 (0.69) | SLC29A1ADORA3CYP3A4TSHRNFKB1 | |
| SCHEMBL27433457 | 0.81 | ADORA3 (0.53) | SLC29A1ADORA3 | |
| SCHEMBL27429372 | 0.81 | SLC29A1 (0.67) | SLC29A1ADORA3CYP3A4TSHRNFKB1 | |
| SCHEMBL27435555 | 0.81 | SLC29A1 (0.67) | SLC29A1ADORA3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024134541-A1 | HETEROCYCLIC COMPOUNDS AS ENT INHIBITORS AND COMPOUNDS FOR USE IN THE TREATMENT OF CANCERS | iTeos Belgium SA (BE) | 2024-06-27 | — | — | WO | disclosed |