Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.59 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833984 | 0.90 | CYP1A2 (0.57) | CYP1A2TLR8CYP2A6TDP1MAOB | |
| SCHEMBL14904215 | 0.89 | CYP1A2 (0.52) | CYP1A2TLR8CYP2A6TDP1MAOB | |
| Ammonia Solution, Strong SCHEMBL27919176 | 0.89 | CYP1A2 (0.55) | CYP1A2TLR8CYP2A6TDP1MAOB | |
| SCHEMBL29506869 | 0.87 | CYP1A2 (0.68) | CYP1A2TLR8CYP2A6TDP1MAOB | |
| SCHEMBL13241132 | 0.86 | MAOB (0.50) | CYP1A2TLR8TDP1MAOBADORA3 | |
| SCHEMBL18561790 | 0.85 | CYP1A2 (0.52) | CYP1A2TLR8CYP2A6TDP1MAOB | |
| SCHEMBL8590628 | 0.85 | CYP1A2 (0.52) | CYP1A2TLR8CYP2A6TDP1MAOB | |
| SCHEMBL14904261 | 0.85 | CYP1A2 (0.47) | CYP1A2TLR8ENPP1NPC1RAB9A | |
| SCHEMBL18308723 | 0.85 | CYP1A2 (0.47) | CYP1A2TLR8CYP2A6TDP1MAOB | |
| SCHEMBL2495608 | 0.83 | ENPP1 (0.57) | CYP2A6MAOBMAOAENPP1ENPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1128126-C | Process for synthesizing alpha-arylnaphthalene and its derivative | GUANGZHOU INST OF CHEMISTRY (CN) | 2003-11-19 | — | — | CN | disclosed |
| CN-1317472-A | Process for synthesizing alpha-arylnaphthalene and its derivative | GUANGZHOU INST OF CHEMISTRY (CN) | 2001-10-17 | — | — | CN | disclosed |