Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27430792 | 0.85 | CYP1A2 (0.59) | CYP1A2ENPP1TLR8NPC1RAB9A | |
| SCHEMBL12405300 | 0.83 | ENPP1 (0.50) | CYP1A2ENPP1KIF11MAPTNPC1 | |
| SCHEMBL14904215 | 0.82 | CYP1A2 (0.52) | CYP1A2ENPP1TLR8NPC1RAB9A | |
| SCHEMBL9990558 | 0.81 | TLR8 (0.56) | SCN9ASCN5ATLR8KIF11MAPT | |
| SCHEMBL27460115 | 0.81 | SCN9A (0.44) | SCN9ASCN5AENPP1TLR8KIF11 | |
| SCHEMBL7833984 | 0.80 | CYP1A2 (0.57) | CYP1A2ENPP1TLR8MAPT | |
| SCHEMBL28224945 | 0.80 | KIF11 (0.52) | SCN9ASCN5AENPP1KIF11CYP2C19 | |
| SCHEMBL14026046 | 0.79 | ENPP1 (0.43) | CYP1A2SCN9ASCN5AENPP1KIF11 | |
| SCHEMBL27525626 | 0.79 | KIF11 (0.47) | CYP1A2SCN9ASCN5AENPP1KIF11 | |
| SCHEMBL18561790 | 0.79 | CYP1A2 (0.52) | CYP1A2SCN9ATLR8MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102617-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2015-08-11 | — | — | US | disclosed |
| US-20130109713-A1 | ANTIMICROBIAL AGENTS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109713-A1 | ANTIMICROBIAL AGENTS | RPS4X, RPS4Y1, MRPL21 | CYP1A2 3899/4885SCN9A 2597/4885SCN5A 3135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.