Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16707503 | 0.78 | HDAC1 (0.39) | HDAC1HDAC6 | |
| SCHEMBL3410281 | 0.72 | ACHE (0.32) | — | |
| SCHEMBL8847064 | 0.71 | ACHE (0.35) | HDAC1HDAC6 | |
| SCHEMBL27583790 | 0.71 | — | — | |
| SCHEMBL27524997 | 0.70 | — | — | |
| SCHEMBL27330382 | 0.70 | HDAC1 (0.31) | HDAC1HDAC6 | |
| Phosphine SCHEMBL27772308 | 0.69 | ACHE (0.33) | HDAC1HDAC6 | |
| SCHEMBL18885784 | 0.67 | HDAC1 (0.32) | HDAC1HDAC6 | |
| SCHEMBL12689887 | 0.67 | HDAC1 (0.37) | HDAC1HDAC6 | |
| SCHEMBL9500636 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1043575-C | Silylated acetylcholinesterase inhibitors | MERRELL DOW PHARMA (US) | 1999-06-09 | — | — | CN | disclosed |