Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 19/20 | 0.61 |
| ▸ | JAK1 | P23458 | 19/20 | 0.61 |
| ▸ | AURKA | O14965 | 1/20 | 0.58 |
| ▸ | PRKCA | P17252 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
| ▸ | TYK2 | P29597 | 4/20 | 0.55 |
| ▸ | JAK3 | P52333 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2280497 | 0.94 | JAK2 (0.66) | JAK2JAK1AURKAPRKCAKDR | |
| SCHEMBL2275731 | 0.90 | JAK2 (0.59) | JAK2JAK1AURKAPRKCAKDR | |
| SCHEMBL2275734 | 0.90 | JAK2 (0.59) | JAK2JAK1AURKAPRKCAKDR | |
| SCHEMBL2275727 | 0.90 | JAK2 (0.59) | JAK2JAK1AURKAPRKCAKDR | |
| SCHEMBL27433394 | 0.89 | JAK1 (0.60) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL25289131 | 0.88 | JAK1 (0.66) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL29460632 | 0.88 | JAK1 (0.66) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL25240987 | 0.88 | JAK1 (0.66) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL9953265 | 0.85 | JAK1 (0.53) | JAK2JAK1AURKAPRKCAKDR | |
| SCHEMBL2282018 | 0.84 | JAK1 (0.54) | JAK2JAK1AURKAPRKCAKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393923-A1 | PYRIDO RING COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATE, COMPOSITION, AND APPLICATION | Yiyou Biotech (Shanghai) Co., Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |