Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 17/20 | 0.60 |
| ▸ | JAK2 | O60674 | 14/20 | 0.60 |
| ▸ | JAK3 | P52333 | 12/20 | 0.56 |
| ▸ | TYK2 | P29597 | 11/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27432005 | 0.89 | JAK2 (0.61) | JAK1JAK2JAK3TYK2 | |
| SCHEMBL2226318 | 0.86 | JAK1 (0.58) | JAK1JAK2JAK3TYK2 | |
| SCHEMBL12424913 | 0.86 | JAK1 (0.68) | JAK1JAK2JAK3TYK2 | |
| SCHEMBL25289131 | 0.85 | JAK1 (0.66) | JAK1JAK2JAK3TYK2 | |
| SCHEMBL25240987 | 0.85 | JAK1 (0.66) | JAK1JAK2JAK3TYK2 | |
| SCHEMBL29460632 | 0.85 | JAK1 (0.66) | JAK1JAK2JAK3TYK2 | |
| SCHEMBL2280497 | 0.83 | JAK2 (0.66) | JAK1JAK2JAK3TYK2 | |
| SCHEMBL27432062 | 0.81 | JAK1 (0.72) | JAK1JAK2JAK3TYK2 | |
| SCHEMBL2282018 | 0.81 | JAK1 (0.54) | JAK1JAK2JAK3TYK2 | |
| SCHEMBL2278015 | 0.81 | JAK1 (0.51) | JAK1JAK2JAK3TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393923-A1 | PYRIDO RING COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATE, COMPOSITION, AND APPLICATION | Yiyou Biotech (Shanghai) Co., Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |