Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 18/20 | 0.69 |
| ▸ | JAK2 | O60674 | 4/20 | 0.69 |
| ▸ | JAK3 | P52333 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25697712 | 0.88 | JAK3 (0.71) | JAK1JAK2JAK3 | |
| SCHEMBL27432062 | 0.88 | JAK1 (0.72) | JAK1JAK2JAK3 | |
| SCHEMBL2292584 | 0.87 | JAK1 (0.74) | JAK1JAK2JAK3 | |
| SCHEMBL27436032 | 0.86 | JAK1 (0.72) | JAK1JAK2JAK3 | |
| SCHEMBL27437445 | 0.86 | JAK1 (0.63) | JAK1JAK2JAK3 | |
| SCHEMBL25698936 | 0.84 | JAK3 (0.66) | JAK1JAK2JAK3 | |
| SCHEMBL27432584 | 0.84 | JAK1 (0.61) | JAK1JAK2JAK3 | |
| SCHEMBL27439929 | 0.84 | JAK1 (0.61) | JAK1JAK2JAK3 | |
| SCHEMBL27439911 | 0.84 | JAK3 (0.65) | JAK1JAK2JAK3 | |
| SCHEMBL27439429 | 0.83 | JAK1 (0.64) | JAK1JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393923-A1 | PYRIDO RING COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATE, COMPOSITION, AND APPLICATION | Yiyou Biotech (Shanghai) Co., Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |