Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 18/20 | 0.64 |
| ▸ | JAK2 | O60674 | 9/20 | 0.64 |
| ▸ | JAK3 | P52333 | 2/20 | 0.58 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27433817 | 0.86 | JAK1 (0.58) | JAK1JAK2JAK3AURKAPRKCA | |
| SCHEMBL27432062 | 0.84 | JAK1 (0.72) | JAK1JAK2JAK3 | |
| SCHEMBL27433678 | 0.83 | JAK1 (0.59) | JAK1JAK2JAK3AURKAPRKCA | |
| SCHEMBL27432020 | 0.83 | JAK1 (0.69) | JAK1JAK2JAK3 | |
| SCHEMBL27439487 | 0.82 | JAK1 (0.62) | JAK1JAK2JAK3 | |
| SCHEMBL25697712 | 0.79 | JAK3 (0.71) | JAK1JAK2JAK3 | |
| SCHEMBL2291834 | 0.79 | JAK1 (0.80) | JAK1JAK2JAK3 | |
| SCHEMBL2226290 | 0.79 | JAK1 (1.00) | JAK1JAK2JAK3AURKAPRKCA | |
| SCHEMBL2297203 | 0.78 | JAK1 (0.81) | JAK1JAK2JAK3AURKAPRKCA | |
| SCHEMBL2292584 | 0.78 | JAK1 (0.74) | JAK1JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393923-A1 | PYRIDO RING COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATE, COMPOSITION, AND APPLICATION | Yiyou Biotech (Shanghai) Co., Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |