Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL10929574 | 1.00 | POLB (0.44) | POLBACP3CYP2C9CYP2C19SRC | |
| Pyrophosphoric Acid SCHEMBL125363 | 0.92 | ACP3 (0.42) | POLBACP3CYP2C9CYP2C19SRC | |
| SCHEMBL1029655 | 0.92 | SLC6A4 (0.39) | POLBSRD5A2FFAR1PPARGPPARA | |
| SCHEMBL10929571 | 0.87 | S1PR1 (0.44) | POLBACP3CYP2C9CYP2C19SRC | |
| SCHEMBL6559226 | 0.87 | S1PR1 (0.44) | POLBACP3CYP2C9CYP2C19SRC | |
| SCHEMBL11174557 | 0.87 | SLC6A4 (0.36) | POLBSRD5A2FFAR1PPARGPPARA | |
| SCHEMBL11426347 | 0.87 | SLC6A4 (0.36) | POLBSRD5A2FFAR1PPARGPPARA | |
| SCHEMBL7638783 | 0.87 | SLC6A4 (0.36) | POLBSRD5A2FFAR1PPARGPPARA | |
| Phosphine SCHEMBL28724360 | 0.85 | SLC6A4 (0.35) | SRD5A2FFAR1 | |
| SCHEMBL27419949 | 0.84 | SLC6A4 (0.34) | POLBSRD5A2FFAR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105462216-A | Glass fiber reinforced and toughened flame-retardant material | QINGDAO YISHIBAO PLASTIC CO LTD | 2016-04-06 | — | — | CN | claimed |
| CN-104845077-A | Flame-retardant and modified PBT composite material and preparation method thereof | QINGDAO WANLI TECHNOLOGY CO LTD | 2015-08-19 | — | — | CN | claimed |
| CN-104845067-A | Inorganic particle filled and modified PBT powder and preparation method thereof | QINGDAO WANLI TECHNOLOGY CO LTD | 2015-08-19 | — | — | CN | claimed |
| CN-104744779-A | Nano carbon fiber modified polyethylene composite material and preparation method thereof | QINGDAO WANLI TECHNOLOGY CO LTD | 2015-07-01 | — | — | CN | claimed |
| CN-104725822-A | Glass-fiber-reinforced PC/PET composite material and preparation method of the glass-fiber-reinforced PC/PET composite material | QINGDAO WANLI TECHNOLOGY CO LTD | 2015-06-24 | — | — | CN | claimed |
| CN-104672868-A | PC/PET defective material reclaimed composition | QINGDAO JIAYIYANG INDUSTRY & TRADE CO LTD | 2015-06-03 | — | — | CN | claimed |
| CN-104650551-A | PC/PBT defective material recovered composition | QINGDAO TONGCHUANG ENERGY SAVING ENVIRONMENTAL PROT ENG CO LTD | 2015-05-27 | — | — | CN | claimed |
| CN-103214808-A | Copier or printer external part using halogen-free flame-retardant resin composition containing regenerated PC and regenerated PET | KONICA MINOLTA BUSINESS TECH | 2013-07-24 | — | — | CN | claimed |
| CN-101475739-B | High gloss, scratch-resistant, halogen-free and flame-retardant polycarbonate resin composition | SHANGHAI KUMHO SUNNY PLASTICS | 2011-09-14 | — | — | CN | claimed |
| CN-101475739-A | High gloss, scratch-resistant, halogen-free and flame-retardant polycarbonate resin composition | SHANGHAI KUMHO SUNNY PLASTICS (CN) | 2009-07-08 | — | — | CN | claimed |
| CN-101469113-A | Halogen-free flame-retardant toughened polycarbonate composition | SHANGHAI GENIUS ADVANCED MAT (CN) | 2009-07-01 | — | — | CN | claimed |
| CN-101412843-A | Flame-retardant polycarbonate and acrylonitrile-butadiene-styrene resin compositions | SHANGHAI RES INST CHEMICAL IND (CN) | 2009-04-22 | — | — | CN | claimed |
| CN-105612035-A | Device for making additives packages ('masterbatch') for thermoplastic compositions | SABIC GLOBAL TECHNOLOGIES BV | 2016-05-25 | — | — | CN | disclosed |
| CN-105555853-A | Thermally conductive flame retardant polymer compositions based on polycarbonate | SABIC INNOVATIVE PLASTICS IP BV | 2016-05-04 | — | — | CN | disclosed |
| CN-105531321-A | Polycarbonate based ductile thermally conductive polymer compositions and uses | SABIC INNOVATIVE PLASTICS IP BV | 2016-04-27 | — | — | CN | disclosed |
| CN-105492214-A | Flame retardant laser direct structuring materials | SABIC INNOVATIVE PLASTICS IP BV | 2016-04-13 | — | — | CN | disclosed |
| CN-1229816-A | Polycarbonate-based flame retardant resin composition | DAICEL CHEM (JP) | 1999-09-29 | — | — | CN | disclosed |
| CN-1226268-A | Flame-retardant molding composition | BASF AG (DE) | 1999-08-18 | — | — | CN | disclosed |
| CN-1216560-A | Thermoplastic moulding materials based on syndiotactic vinylaromatic polymers, low-viscosity polyamides and polyphenylene ethers modified with polar groups | BASF AG (DE) | 1999-05-12 | — | — | CN | disclosed |
| CN-1190409-A | Antidrip agents for thermoplastic molding compounds | BASF AG (DE) | 1998-08-12 | — | — | CN | disclosed |